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Friday 24 February 2012

Science: a many-flavoured thing

It is normal to expect researchers to be comfortable when handling their study organisms, but where do you draw the line in terms of 'familiarity'? Personally, I would draw the line at basic handling and post-mortem dissections. Valerie Clark, a herpetologist studying frog toxins, has a different level of familiarity with her study organisms: back-licking! By licking frogs she can determine whether they are poisonous by the taste of their skin secretions. (Note: I do not recommend non-experts pick up frogs and lick them to see if they are poisonous). Most skin secretions of poisonous frogs can't kill a human, but it can cause throat burning and constriction, but when in the field with limited equipment, often the only way to tell whether you've found a poisonous frog is to give it a hearty lick on the back.

Poisonous Mantella frogs from Madagascar taste bitter-sweet

In a recent study, Clark used electrical stimulation to extract skin secretions from some poisonous frogs found in Madagascar. Apparently, licking these study frogs leaves a bitter-sweet taste. The reason for this taste is revealed by mass spectrometry of the secretion products: sucrose and a new bile (or stomach) acid called tauromantellic acid. Frogs typically don't generate their own poison, their guts actually sequester and remove it from insects that they eat so they themselves are not poisoned. Clark believes that the bile acid on the skin is involved in transporting toxins from the frog's gut to its skin. FYI: this does not happen in humans, if you eat something particularly nasty and don't seek medical help, it is likely you will just die. On that happy note, frogs are cute anyway, so who wouldn't want to lick them?!
Original article via National Geographic News.

2 comments:

  1. surely there are indicator strips like the ones diabetics used to use to test for sugar in their urine, rather than run the risk by licking the frog. also how quantifiable is a "lick", surely you want to use an indicator that is measurable. mmmmm

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  2. I agree, it would be much healthier for all involved if there was some version of poison "litmus". I believe many poisonous frogs tend to have highly alkaline skin, so it is possible. What is a little unnerving is that with chytrid fungus being so readily spread, what would be the time allowed between licking different frogs? Would one have to drink alcohol between licking different frogs to sanitise the tongue?
    The products of the poison are analysed using mass spec., so I don't think "licks" are used as a quantifier, but rather, an identifier of poisonous frogs in the field.

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